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Epigenetic Regulation of Individual Modules of the immunoglobulin heavy chain locus 3′ Regulatory Region
The Igh locus undergoes an amazing array of DNA rearrangements and modifications during B cell development. During early stages, the variable region gene is constructed from constituent variable (V), diversity (D), and joining (J) segments (VDJ joining). B cells that successfully express an antibody...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000994/ https://www.ncbi.nlm.nih.gov/pubmed/24795714 http://dx.doi.org/10.3389/fimmu.2014.00163 |