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Clinical and Biomarker Changes in Premanifest Huntington Disease Show Trial Feasibility: A Decade of the PREDICT-HD Study

There is growing consensus that intervention and treatment of Huntington disease (HD) should occur at the earliest stage possible. Various early-intervention methods for this fatal neurodegenerative disease have been identified, but preventive clinical trials for HD are limited by a lack of knowledg...

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Detalles Bibliográficos
Autores principales: Paulsen, Jane S., Long, Jeffrey D., Johnson, Hans J., Aylward, Elizabeth H., Ross, Christopher A., Williams, Janet K., Nance, Martha A., Erwin, Cheryl J., Westervelt, Holly J., Harrington, Deborah L., Bockholt, H. Jeremy, Zhang, Ying, McCusker, Elizabeth A., Chiu, Edmond M., Panegyres, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000999/
https://www.ncbi.nlm.nih.gov/pubmed/24795630
http://dx.doi.org/10.3389/fnagi.2014.00078