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Erk5 is a mediator to TGFβ1-induced loss of phenotype and function in human podocytes
Background: Podocytes are highly specialized cells integral to the normal functioning kidney, however, in diabetic nephropathy injury occurs leading to a compromised phenotype and podocyte dysfunction which critically produces podocyte loss with subsequent renal impairment. TGFβ1 holds a major role...
Autores principales: | Badshah, Irbaz I., Baines, Deborah L., Dockrell, Mark E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001011/ https://www.ncbi.nlm.nih.gov/pubmed/24795631 http://dx.doi.org/10.3389/fphar.2014.00071 |
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