Mutations of Cx43 that affect B cell spreading in response to BCR signaling

The gap junction (GJ) protein connexin 43 (Cx43) is both necessary and sufficient for B cell receptor (BCR)-mediated cell spreading. To address how Cx43 mediates this effect, we blocked its function genetically, by expressing mutants of Cx43, and pharmacologically, by using chemical inhibitors. Whil...

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Detalles Bibliográficos
Autores principales: Falk, Letitia, Dang-Lawson, May, Vega, José Luis, Pournia, Farnaz, Choi, Kate, Jang, Caren, Naus, Christian C., Matsuuchi, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001238/
https://www.ncbi.nlm.nih.gov/pubmed/24526714
http://dx.doi.org/10.1242/bio.20147328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001238/
https://www.ncbi.nlm.nih.gov/pubmed/24526714
http://dx.doi.org/10.1242/bio.20147328

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