Agonist antibodies activating the Met receptor protect cardiomyoblasts from cobalt chloride-induced apoptosis and autophagy

Met, the tyrosine kinase receptor for hepatocyte growth factor (HGF), mainly activates prosurvival pathways, including protection from apoptosis. In this work, we investigated the cardioprotective mechanisms of Met activation by agonist monoclonal antibodies (mAbs). Cobalt chloride (CoCl(2)), a chem...

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Detalles Bibliográficos
Autores principales: Gallo, S, Gatti, S, Sala, V, Albano, R, Costelli, P, Casanova, E, Comoglio, P M, Crepaldi, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001309/
https://www.ncbi.nlm.nih.gov/pubmed/24743740
http://dx.doi.org/10.1038/cddis.2014.155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001309/
https://www.ncbi.nlm.nih.gov/pubmed/24743740
http://dx.doi.org/10.1038/cddis.2014.155

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