Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD

The pathogenic mechanisms underlying the progression of non-alcoholic fatty liver disease (NAFLD) are not fully understood. In this study, we aimed to assess the relationship between endoplasmic reticulum (ER) stress and autophagy in human and mouse hepatocytes during NAFLD. ER stress and autophagy...

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Detalles Bibliográficos
Autores principales: González-Rodríguez, Á, Mayoral, R, Agra, N, Valdecantos, M P, Pardo, V, Miquilena-Colina, M E, Vargas-Castrillón, J, Lo Iacono, O, Corazzari, M, Fimia, G M, Piacentini, M, Muntané, J, Boscá, L, García-Monzón, C, Martín-Sanz, P, Valverde, Á M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001315/
https://www.ncbi.nlm.nih.gov/pubmed/24743734
http://dx.doi.org/10.1038/cddis.2014.162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001315/
https://www.ncbi.nlm.nih.gov/pubmed/24743734
http://dx.doi.org/10.1038/cddis.2014.162

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