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DNA polymerase V activity is autoregulated by a novel intrinsic DNA-dependent ATPase
Escherichia coli DNA polymerase V (pol V), a heterotrimeric complex composed of UmuD′(2)C, is marginally active. ATP and RecA play essential roles in the activation of pol V for DNA synthesis including translesion synthesis (TLS). We have established three features of the roles of ATP and RecA. (1)...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001326/ https://www.ncbi.nlm.nih.gov/pubmed/24843026 http://dx.doi.org/10.7554/eLife.02384 |