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Lactosylceramide promotes hypertrophy through ROS generation and activation of ERK1/2 in cardiomyocytes
Hypertrophy is central to several heart diseases; however, not much is known about the role of glycosphingolipids (GSLs) in this phenotype. Since GSLs have been accorded several physiological functions, we sought to determine whether these compounds affect cardiac hypertrophy. By using a rat cardiom...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001711/ https://www.ncbi.nlm.nih.gov/pubmed/24658420 http://dx.doi.org/10.1093/glycob/cwu020 |