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Sodium channel selectivity and conduction: Prokaryotes have devised their own molecular strategy

Striking structural differences between voltage-gated sodium (Nav) channels from prokaryotes (homotetramers) and eukaryotes (asymmetric, four-domain proteins) suggest the likelihood of different molecular mechanisms for common functions. For these two channel families, our data show similar selectiv...

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Detalles Bibliográficos
Autores principales: Finol-Urdaneta, Rocio K., Wang, Yibo, Al-Sabi, Ahmed, Zhao, Chunfeng, Noskov, Sergei Y., French, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001777/
https://www.ncbi.nlm.nih.gov/pubmed/24420772
http://dx.doi.org/10.1085/jgp.201311037