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Finding the sources of missing heritability in a yeast cross

For many traits, including susceptibility to common diseases in humans, causal loci uncovered by genetic mapping studies explain only a minority of the heritable contribution to trait variation. Multiple explanations for this “missing heritability” have been proposed(1). Here we use a large cross be...

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Detalles Bibliográficos
Autores principales: Bloom, Joshua S., Ehrenreich, Ian M., Loo, Wesley, Võ Lite, Thúy-Lan, Kruglyak, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001867/
https://www.ncbi.nlm.nih.gov/pubmed/23376951
http://dx.doi.org/10.1038/nature11867