Multiple Functional Motifs Are Required for the Tumor Suppressor Activity of a Constitutively-Active ErbB4 Mutant

ErbB4 (HER4) is a member of the ErbB family of receptor tyrosine kinases, which includes the Epidermal Growth Factor Receptor (EGFR/ErbB1), ErbB2 (HER2/Neu), and ErbB3 (HER3). Mounting evidence indicates that ErbB4, unlike EGFR or ErbB2, functions as a tumor suppressor in many human malignancies. Pr...

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Detalles Bibliográficos
Autores principales: Gallo, Richard M., Bryant, Ianthe N., Mill, Christopher P., Kaverman, Steven, Riese, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002051/
https://www.ncbi.nlm.nih.gov/pubmed/24791013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002051/
https://www.ncbi.nlm.nih.gov/pubmed/24791013

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