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Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargo

A novel method for the parallel synthesis of peptide-biocargo conjugates was developed that utilizes affinity purification for fast isolation of the conjugates in order to avoid time consuming HPLC purification. The methodology was applied to create two libraries of cell-penetrating peptide (CPP)–PN...

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Detalles Bibliográficos
Autores principales: Deuss, Peter J., Arzumanov, Andrey A., Williams, Donna L., Gait, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002126/
https://www.ncbi.nlm.nih.gov/pubmed/24105028
http://dx.doi.org/10.1039/c3ob41659c