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A novel minigene scaffold for therapeutic cancer vaccines

Genetic vaccines are emerging as a powerful modality to induce T-cell responses to target tumor associated antigens (TAA). Viral or plasmid DNA or RNA vectors harbor an expression cassette encoding the antigen of choice delivered in vivo by vaccination. In this context, immunizations with minigenes...

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Detalles Bibliográficos
Autores principales: Aurisicchio, Luigi, Fridman, Arthur, Bagchi, Ansuman, Scarselli, Elisa, La Monica, Nicola, Ciliberto, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002591/
https://www.ncbi.nlm.nih.gov/pubmed/24790791
http://dx.doi.org/10.4161/onci.27529