Eomesodermin is required for antitumor immunity mediated by 4-1BB-agonist immunotherapy

CD8(+) T cells in progressing tumors frequently fail to mount an effective antitumor response often in association with the expression of inhibitory receptors, including programmed cell death-1 (PD-1) and lymphocyte-activation gene 3 (Lag3). Using a lymphoma tumor model, we demonstrate that tumor-in...

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Detalles Bibliográficos
Autores principales: Song, Chang, Sadashivaiah, Kavitha, Furusawa, Aki, Davila, Eduardo, Tamada, Koji, Banerjee, Arnob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002624/
https://www.ncbi.nlm.nih.gov/pubmed/24790793
http://dx.doi.org/10.4161/onci.27680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002624/
https://www.ncbi.nlm.nih.gov/pubmed/24790793
http://dx.doi.org/10.4161/onci.27680

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