Cargando…

Prohibitin is required for transcriptional repression by the WT1-BASP1 complex

The Wilms’ tumor 1 protein (WT1) is a transcriptional regulator that can either activate or repress genes controlling cell growth, apoptosis and differentiation. The transcriptional corepressor BASP1 interacts with WT1 and mediates WT1's transcriptional repression activity. BASP1 is contained w...

Descripción completa

Detalles Bibliográficos
Autores principales: Toska, Eneda, Shandilya, Jayasha, Goodfellow, Sarah J., Medler, Kathryn F., Roberts, Stefan G. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002674/
https://www.ncbi.nlm.nih.gov/pubmed/24166496
http://dx.doi.org/10.1038/onc.2013.447