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Clinical and comparative utility of afatinib in non-small cell lung cancer

The first targeted agents approved for non-small cell lung cancer (NSCLC) treatment, the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) gefitinib and erlotinib, have an impressive activity in the presence of activating mutations of the EGFR gene. However, all patients deve...

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Detalles Bibliográficos
Autores principales: D’Arcangelo, Manolo, Hirsch, Fred R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003149/
https://www.ncbi.nlm.nih.gov/pubmed/24790411
http://dx.doi.org/10.2147/BTT.S40567