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The cytoplasmic cage domain of the mechanosensitive channel MscS is a sensor of macromolecular crowding

Cells actively regulate the macromolecular excluded volume of the cytoplasm to maintain the reciprocal fraction of free aqueous solution that is optimal for intracellular processes. However, the mechanisms whereby cells sense this critical parameter remain unclear. The mechanosensitive channel of sm...

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Detalles Bibliográficos
Autores principales: Rowe, Ian, Anishkin, Andriy, Kamaraju, Kishore, Yoshimura, Kenjiro, Sukharev, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003192/
https://www.ncbi.nlm.nih.gov/pubmed/24778428
http://dx.doi.org/10.1085/jgp.201311114