Vinculin phosphorylation differentially regulates mechanotransduction at cell–cell and cell–matrix adhesions

Cells experience mechanical forces throughout their lifetimes. Vinculin is critical for transmitting these forces, yet how it achieves its distinct functions at cell–cell and cell–matrix adhesions remains unanswered. Here, we show vinculin is phosphorylated at Y822 in cell–cell, but not cell–matrix,...

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Detalles Bibliográficos
Autores principales: Bays, Jennifer L., Peng, Xiao, Tolbert, Catlin E., Guilluy, Christophe, Angell, Ashley E., Pan, Yuan, Superfine, Richard, Burridge, Keith, DeMali, Kris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003237/
https://www.ncbi.nlm.nih.gov/pubmed/24751539
http://dx.doi.org/10.1083/jcb.201309092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003237/
https://www.ncbi.nlm.nih.gov/pubmed/24751539
http://dx.doi.org/10.1083/jcb.201309092

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