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Dystrophic muscle environment induces changes in cell plasticity

Fibro-adipogenic progenitors (FAPs) reside in the muscle, where they facilitate myofiber regeneration. Under normal conditions, FAPs lack myogenic potential and thus do not directly contribute to regenerated myofibers. Surprisingly, Saccone and colleagues (pp. 841–857) demonstrated that the dystroph...

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Detalles Bibliográficos
Autores principales: Faralli, Herve, Dilworth, F. Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003273/
https://www.ncbi.nlm.nih.gov/pubmed/24736840
http://dx.doi.org/10.1101/gad.241182.114