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Dystrophic muscle environment induces changes in cell plasticity
Fibro-adipogenic progenitors (FAPs) reside in the muscle, where they facilitate myofiber regeneration. Under normal conditions, FAPs lack myogenic potential and thus do not directly contribute to regenerated myofibers. Surprisingly, Saccone and colleagues (pp. 841–857) demonstrated that the dystroph...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003273/ https://www.ncbi.nlm.nih.gov/pubmed/24736840 http://dx.doi.org/10.1101/gad.241182.114 |