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DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos

Methylation of DNA is an essential epigenetic control mechanism in mammals. During embryonic development, cells are directed toward their future lineages, and DNA methylation poses a fundamental epigenetic barrier that guides and restricts differentiation and prevents regression into an undifferenti...

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Detalles Bibliográficos
Autores principales: Messerschmidt, Daniel M., Knowles, Barbara B., Solter, Davor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003274/
https://www.ncbi.nlm.nih.gov/pubmed/24736841
http://dx.doi.org/10.1101/gad.234294.113