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DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos
Methylation of DNA is an essential epigenetic control mechanism in mammals. During embryonic development, cells are directed toward their future lineages, and DNA methylation poses a fundamental epigenetic barrier that guides and restricts differentiation and prevents regression into an undifferenti...
Autores principales: | Messerschmidt, Daniel M., Knowles, Barbara B., Solter, Davor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003274/ https://www.ncbi.nlm.nih.gov/pubmed/24736841 http://dx.doi.org/10.1101/gad.234294.113 |
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