The diabetes gene Hhex maintains δ-cell differentiation and islet function

The homeodomain transcription factor HHEX (hematopoietically expressed homeobox) has been repeatedly linked to type 2 diabetes mellitus (T2DM) using genome-wide association studies. We report here that within the adult endocrine pancreas, Hhex is selectively expressed in the somatostatin-secreting δ...

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Detalles Bibliográficos
Autores principales: Zhang, Jia, McKenna, Lindsay B., Bogue, Clifford W., Kaestner, Klaus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003275/
https://www.ncbi.nlm.nih.gov/pubmed/24736842
http://dx.doi.org/10.1101/gad.235499.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003275/
https://www.ncbi.nlm.nih.gov/pubmed/24736842
http://dx.doi.org/10.1101/gad.235499.113

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