miR-99a/100∼125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt signaling

Although regulation of stem cell homeostasis by microRNAs (miRNAs) is well studied, it is unclear how individual miRNAs genomically encoded within an organized polycistron can interact to induce an integrated phenotype. miR-99a/100, let-7, and miR-125b paralogs are encoded in two tricistrons on huma...

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Detalles Bibliográficos
Autores principales: Emmrich, Stephan, Rasche, Mareike, Schöning, Jennifer, Reimer, Christina, Keihani, Sarva, Maroz, Aliaksandra, Xie, Ying, Li, Zhe, Schambach, Axel, Reinhardt, Dirk, Klusmann, Jan-Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003278/
https://www.ncbi.nlm.nih.gov/pubmed/24736844
http://dx.doi.org/10.1101/gad.233791.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003278/
https://www.ncbi.nlm.nih.gov/pubmed/24736844
http://dx.doi.org/10.1101/gad.233791.113

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