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The randomised clinical trial and the hazard ratio – medical research’s Emperor’s New Clothes?

As the enthusiasm for individualized treatment and targeted therapies continues to gain momentum, it seems timely to re-assess whether our current research tools are fit for purpose. Randomized Clinical Trials compare groups of patients, the Hazard Ratio is a ‘group summary statistic’, and modeling...

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Detalles Bibliográficos
Autores principales: Stephens, Richard, Stewart, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003285/
https://www.ncbi.nlm.nih.gov/pubmed/24731512
http://dx.doi.org/10.1186/1471-2407-14-260