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Thermal-triggerd Proteinquake Leads to Disassembly of DegP Hexamer as an Imperative Activation Step

The Escherichia coli DegP has been reported to function both as molecular chaperone and protease for the quality control of outer membrane protein biogenesis. Activation of the inactive DegP hexamers was believed to occur via their disassembly into trimeric units and subsequent reassembly into large...

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Detalles Bibliográficos
Autores principales: Li, Shanshan, Wang, Rui, Li, Deyong, Ma, Jing, Li, Heng, He, Xiaochuan, Chang, Zengyi, Weng, Yuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003476/
https://www.ncbi.nlm.nih.gov/pubmed/24776652
http://dx.doi.org/10.1038/srep04834