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Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation

Aging is thought to be associated with increased molecular damage, but representative markers vary across conditions and organisms, making it difficult to assess properties of cumulative damage throughout lifespan. We used nontargeted metabolite profiling to follow age-associated trajectories of >...

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Detalles Bibliográficos
Autores principales: Avanesov, Andrei S, Ma, Siming, Pierce, Kerry A, Yim, Sun Hee, Lee, Byung Cheon, Clish, Clary B, Gladyshev, Vadim N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003482/
https://www.ncbi.nlm.nih.gov/pubmed/24843015
http://dx.doi.org/10.7554/eLife.02077