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Low copy target detection by Droplet Digital PCR through application of a novel open access bioinformatic pipeline, ‘definetherain’
Droplet Digital PCR (ddPCR) represents a new and alternative platform to conventional quantitative-PCR (qPCR) for the quantitation of DNA templates. However, the proposed improvement in sensitivity and reproducibility offered by ddPCR is not yet fully proven, partly because the delineation between p...
Autores principales: | Jones, Mathew, Williams, James, Gärtner, Kathleen, Phillips, Rodney, Hurst, Jacob, Frater, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier/North-Holland Biomedical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003534/ https://www.ncbi.nlm.nih.gov/pubmed/24598230 http://dx.doi.org/10.1016/j.jviromet.2014.02.020 |
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