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Improved linkage analysis of Quantitative Trait Loci using bulk segregants unveils a novel determinant of high ethanol tolerance in yeast

BACKGROUND: Bulk segregant analysis (BSA) coupled to high throughput sequencing is a powerful method to map genomic regions related with phenotypes of interest. It relies on crossing two parents, one inferior and one superior for a trait of interest. Segregants displaying the trait of the superior p...

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Detalles Bibliográficos
Autores principales: Duitama, Jorge, Sánchez-Rodríguez, Aminael, Goovaerts, Annelies, Pulido-Tamayo, Sergio, Hubmann, Georg, Foulquié-Moreno, María R, Thevelein, Johan M, Verstrepen, Kevin J, Marchal, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003806/
https://www.ncbi.nlm.nih.gov/pubmed/24640961
http://dx.doi.org/10.1186/1471-2164-15-207