Genome-scale metabolic network reconstruction of Saccharopolyspora spinosa for Spinosad Production improvement

BACKGROUND: Spinosad is a macrolide antibiotic produced by Saccharopolyspora spinosa with aerobic fermentation. However, the wild strain has a low productivity. In this article, a computational guided engineering approach was adopted in order to improve the yield of spinosad in S. spinosa. RESULTS:...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyang, Zhang, Chuanbo, Wang, Meiling, Lu, Wenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003821/
https://www.ncbi.nlm.nih.gov/pubmed/24628959
http://dx.doi.org/10.1186/1475-2859-13-41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003821/
https://www.ncbi.nlm.nih.gov/pubmed/24628959
http://dx.doi.org/10.1186/1475-2859-13-41

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