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Mitochondrial Aging and Age-Related Dysfunction of Mitochondria

Age-related changes in mitochondria are associated with decline in mitochondrial function. With advanced age, mitochondrial DNA volume, integrity and functionality decrease due to accumulation of mutations and oxidative damage induced by reactive oxygen species (ROS). In aged subjects, mitochondria...

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Detalles Bibliográficos
Autores principales: Chistiakov, Dimitry A., Sobenin, Igor A., Revin, Victor V., Orekhov, Alexander N., Bobryshev, Yuri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003832/
https://www.ncbi.nlm.nih.gov/pubmed/24818134
http://dx.doi.org/10.1155/2014/238463