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Mitochondrial Aging and Age-Related Dysfunction of Mitochondria
Age-related changes in mitochondria are associated with decline in mitochondrial function. With advanced age, mitochondrial DNA volume, integrity and functionality decrease due to accumulation of mutations and oxidative damage induced by reactive oxygen species (ROS). In aged subjects, mitochondria...
Autores principales: | Chistiakov, Dimitry A., Sobenin, Igor A., Revin, Victor V., Orekhov, Alexander N., Bobryshev, Yuri V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003832/ https://www.ncbi.nlm.nih.gov/pubmed/24818134 http://dx.doi.org/10.1155/2014/238463 |
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