Metabolic flux responses to genetic modification for shikimic acid production by Bacillus subtilis strains

BACKGROUND: Shikimic acid (SA) is a key chiral starting molecule for the synthesis of the neuramidase inhibitor GS4104 against viral influenza. Microbial production of SA has been extensively investigated in Escherichia coli, and to a less extent in Bacillus subtilis. However, metabolic flux of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Dong-Feng, Ai, Guo-Min, Zheng, Qing-Xiang, Liu, Chang, Jiang, Cheng-Ying, Liu, Li-Xia, Zhang, Bo, Liu, Yi-Ming, Yang, Chen, Liu, Shuang-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003833/
https://www.ncbi.nlm.nih.gov/pubmed/24628944
http://dx.doi.org/10.1186/1475-2859-13-40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003833/
https://www.ncbi.nlm.nih.gov/pubmed/24628944
http://dx.doi.org/10.1186/1475-2859-13-40

Ejemplares similares