Using a large-scale knowledge database on reactions and regulations to propose key upstream regulators of various sets of molecules participating in cell metabolism

BACKGROUND: Most of the existing methods to analyze high-throughput data are based on gene ontology principles, providing information on the main functions and biological processes. However, these methods do not indicate the regulations behind the biological pathways. A critical point in this contex...

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Detalles Bibliográficos
Autores principales: Blavy, Pierre, Gondret, Florence, Lagarrigue, Sandrine, van Milgen, Jaap, Siegel, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004165/
https://www.ncbi.nlm.nih.gov/pubmed/24635915
http://dx.doi.org/10.1186/1752-0509-8-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004165/
https://www.ncbi.nlm.nih.gov/pubmed/24635915
http://dx.doi.org/10.1186/1752-0509-8-32

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