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Attenuation of inflammatory polyarthritis in TNF transgenic mice by diacerein: comparative analysis with dexamethasone, methotrexate and anti-TNF protocols

The impact of diacerein, an effective cartilage targeted therapy that is used in patients with osteoarthritis, on the development and progression of chronic inflammatory arthritis was evaluated in a tumor necrosis factor (TNF) transgenic mouse model (Tg197). The response to diacerein at 2, 20, or 60...

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Detalles Bibliográficos
Autores principales: Douni, Eleni, Sfikakis, Petros P, Haralambous, Sylva, Fernandes, Peter, Kollias, George
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400419/
https://www.ncbi.nlm.nih.gov/pubmed/14979939
http://dx.doi.org/10.1186/ar1028