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X-ray Crystallographic Structures of Trimers and Higher-Order Oligomeric Assemblies of a Peptide Derived from Aβ(17–36)

[Image: see text] A peptide derived from Aβ(17–36) crystallizes to form trimers that further associate to form higher-order oligomers. The trimers consist of three highly twisted β-hairpins in a triangular arrangement. Two trimers associate face-to-face in the crystal lattice to form a hexamer; four...

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Detalles Bibliográficos
Autores principales: Spencer, Ryan K., Li, Hao, Nowick, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004244/
https://www.ncbi.nlm.nih.gov/pubmed/24669800
http://dx.doi.org/10.1021/ja5017409