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Nanoparticle-Delivered Transforming Growth Factor-β siRNA Enhances Vaccination against Advanced Melanoma by Modifying Tumor Microenvironment

[Image: see text] Achievement of potent immunoresponses against self/tumor antigens and effective therapeutic outcome against advanced tumors remain major challenges in cancer immunotherapy. The specificity and efficiency of two nanoparticle-based delivery systems, lipid-calcium-phosphate (LCP) nano...

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Detalles Bibliográficos
Autores principales: Xu, Zhenghong, Wang, Yuhua, Zhang, Lu, Huang, Leaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004320/
https://www.ncbi.nlm.nih.gov/pubmed/24580381
http://dx.doi.org/10.1021/nn500216y