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Ovariectomized rats as a model of postmenopausal osteoarthritis: validation and application

We aimed to assess the effect of ovariectomy on cartilage turnover and degradation, to evaluate whether ovariectomized (OVX) rats could form an experimental model of postmenopausal osteoarthritis. The effect of ovariectomy on cartilage was studied using two cohorts of female Sprague–Dawley rats, age...

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Detalles Bibliográficos
Autores principales: Høegh-Andersen, Pernille, Tankó, László B, Andersen, Thomas L, Lundberg, Carina V, Mo, John A, Heegaard, Anne-Marie, Delaissé, Jean-Marie, Christgau, Stephan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400436/
https://www.ncbi.nlm.nih.gov/pubmed/15059281
http://dx.doi.org/10.1186/ar1152