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Structural Basis for the Immunomodulatory Function of Cysteine Protease Inhibitor from Human Roundworm Ascaris lumbricoides

Immunosuppression associated with infections of nematode parasites has been documented. Cysteine protease inhibitor (CPI) released by the nematode parasites is identified as one of the major modulators of host immune response. In this report, we demonstrated that the recombinant CPI protein of Ascar...

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Detalles Bibliográficos
Autores principales: Mei, Guoqiang, Dong, Jianmei, Li, Zhaotao, Liu, Sanling, Liu, Yunfeng, Sun, Mingze, Liu, Guiyun, Su, Zhong, Liu, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004552/
https://www.ncbi.nlm.nih.gov/pubmed/24781326
http://dx.doi.org/10.1371/journal.pone.0096069