Lung Remodeling in a Mouse Model of Asthma Involves a Balance between TGF-β1 and BMP-7

A key event in chronic allergic asthma is the TGF-β-induced activation of fibroblasts into α-SMA-positive myofibroblasts which synthesize type-I collagen. In the present study we investigated the effect of the anti-fibrotic molecule BMP-7 in asthma. Balb/c mice were immunized i.p. with ovalbumin in...

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Detalles Bibliográficos
Autores principales: Stumm, Camila Leindecker, Halcsik, Erik, Landgraf, Richardt Gama, Camara, Niels Olsen Saraiva, Sogayar, Mari Cleide, Jancar, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004563/
https://www.ncbi.nlm.nih.gov/pubmed/24781156
http://dx.doi.org/10.1371/journal.pone.0095959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004563/
https://www.ncbi.nlm.nih.gov/pubmed/24781156
http://dx.doi.org/10.1371/journal.pone.0095959

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