Cargando…

A Pilot Genome-Scale Profiling of DNA Methylation in Sporadic Pituitary Macroadenomas: Association with Tumor Invasion and Histopathological Subtype

Pituitary adenomas (PAs) are neoplasms that may cause a variety of neurological and endocrine effects. Although known causal contributors include heredity, hormonal influence and somatic mutations, the pathophysiologic mechanisms driving tumorigenesis and invasion of sporadic PAs remain unknown. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Ling, Chao, Pease, Matthew, Shi, Lingling, Punj, Vasu, Shiroishi, Mark S., Commins, Deborah, Weisenberger, Daniel J., Wang, Kai, Zada, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004564/
https://www.ncbi.nlm.nih.gov/pubmed/24781529
http://dx.doi.org/10.1371/journal.pone.0096178