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A Pilot Genome-Scale Profiling of DNA Methylation in Sporadic Pituitary Macroadenomas: Association with Tumor Invasion and Histopathological Subtype
Pituitary adenomas (PAs) are neoplasms that may cause a variety of neurological and endocrine effects. Although known causal contributors include heredity, hormonal influence and somatic mutations, the pathophysiologic mechanisms driving tumorigenesis and invasion of sporadic PAs remain unknown. We...
Autores principales: | Ling, Chao, Pease, Matthew, Shi, Lingling, Punj, Vasu, Shiroishi, Mark S., Commins, Deborah, Weisenberger, Daniel J., Wang, Kai, Zada, Gabriel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004564/ https://www.ncbi.nlm.nih.gov/pubmed/24781529 http://dx.doi.org/10.1371/journal.pone.0096178 |
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