Recombinase-Mediated Reprogramming and Dystrophin Gene Addition in mdx Mouse Induced Pluripotent Stem Cells

A cell therapy strategy utilizing genetically-corrected induced pluripotent stem cells (iPSC) may be an attractive approach for genetic disorders such as muscular dystrophies. Methods for genetic engineering of iPSC that emphasize precision and minimize random integration would be beneficial. We dem...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Chunli, Farruggio, Alfonso P., Bjornson, Christopher R. R., Chavez, Christopher L., Geisinger, Jonathan M., Neal, Tawny L., Karow, Marisa, Calos, Michele P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004573/
https://www.ncbi.nlm.nih.gov/pubmed/24781921
http://dx.doi.org/10.1371/journal.pone.0096279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004573/
https://www.ncbi.nlm.nih.gov/pubmed/24781921
http://dx.doi.org/10.1371/journal.pone.0096279

Ejemplares similares