Nuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activity

The nuclear pore complex (NPC) has dual roles in nucleocytoplasmic transport and chromatin organization. In many eukaryotes the coiled-coil Mlp/Tpr proteins of the NPC nuclear basket have specific functions in interactions with chromatin and defining specialized regions of active transcription, wher...

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Detalles Bibliográficos
Autores principales: Holden, Jennifer M., Koreny, Ludek, Obado, Samson, Ratushny, Alexander V., Chen, Wei-Ming, Chiang, Jung-Hsien, Kelly, Steven, Chait, Brian T., Aitchison, John D., Rout, Michael P., Field, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004592/
https://www.ncbi.nlm.nih.gov/pubmed/24600046
http://dx.doi.org/10.1091/mbc.E13-12-0750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004592/
https://www.ncbi.nlm.nih.gov/pubmed/24600046
http://dx.doi.org/10.1091/mbc.E13-12-0750

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