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Nuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activity
The nuclear pore complex (NPC) has dual roles in nucleocytoplasmic transport and chromatin organization. In many eukaryotes the coiled-coil Mlp/Tpr proteins of the NPC nuclear basket have specific functions in interactions with chromatin and defining specialized regions of active transcription, wher...
Autores principales: | Holden, Jennifer M., Koreny, Ludek, Obado, Samson, Ratushny, Alexander V., Chen, Wei-Ming, Chiang, Jung-Hsien, Kelly, Steven, Chait, Brian T., Aitchison, John D., Rout, Michael P., Field, Mark C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004592/ https://www.ncbi.nlm.nih.gov/pubmed/24600046 http://dx.doi.org/10.1091/mbc.E13-12-0750 |
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