The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis

T-cell immunoglobulin mucin protein 4 (TIM4), a phosphatidylserine (PtdSer)-binding receptor, mediates the phagocytosis of apoptotic cells. How TIM4 exerts its function is unclear, and conflicting data have emerged. To define the mode of action of TIM4, we used two distinct but complementary approac...

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Detalles Bibliográficos
Autores principales: Flannagan, Ronald S., Canton, Johnathan, Furuya, Wendy, Glogauer, Michael, Grinstein, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004599/
https://www.ncbi.nlm.nih.gov/pubmed/24623723
http://dx.doi.org/10.1091/mbc.E13-04-0212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004599/
https://www.ncbi.nlm.nih.gov/pubmed/24623723
http://dx.doi.org/10.1091/mbc.E13-04-0212

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