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Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer

Lung cancer evades host immune surveillance by dysregulating inflammation. Tumors and their surrounding stromata produce growth factors, cytokines, and chemokines that recruit, expand, and/or activate myeloid-derived suppressor cells (MDSCs). MDSCs regulate immune responses and are frequently found...

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Detalles Bibliográficos
Autores principales: Srivastava, Minu K, Zhu, Li, Harris-White, Marni, Huang, Min, St John, Maie, Lee, Jay M, Salgia, Ravi, Cameron, Robert B, Strieter, Robert, Dubinett, Steven, Sharma, Sherven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004632/
https://www.ncbi.nlm.nih.gov/pubmed/24791250
http://dx.doi.org/10.2147/ITT.S32617