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The SORL1 Gene and Convergent Neural Risk for Alzheimer's Disease Across the Human Lifespan

Prior to intervention trials in individuals genetically at-risk for late-onset Alzheimer's disease, critical first steps are identifying where (neuroanatomic effects), when (timepoint in the lifespan) and how (gene expression and neuropathology) Alzheimer's risk genes impact the brain. We...

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Detalles Bibliográficos
Autores principales: Felsky, Daniel, Szeszko, Philip, Yu, Lei, Honer, William G, De Jager, Philip L, Schneider, Julie A, Malhotra, Anil K, Lencz, Todd, Ikuta, Toshikazu, Pipitone, Jon, Chakravarty, M Mallar, Lobaugh, Nancy J, Mulsant, Benoit H, Pollock, Bruce G, Kennedy, James L, Bennett, David A, Voineskos, Aristotle N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004725/
https://www.ncbi.nlm.nih.gov/pubmed/24166411
http://dx.doi.org/10.1038/mp.2013.142