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SMCHD1 accumulates at DNA damage sites and facilitates the repair of DNA double-strand breaks

SMCHD1 is a structural maintenance of chromosomes (SMC) family protein involved in epigenetic gene silencing and chromosome organisation on the female inactive X chromosome and at a limited number of autosomal loci. Here, we demonstrate that SMCHD1 also has a role in DNA repair of double-strand brea...

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Detalles Bibliográficos
Autores principales: Coker, Heather, Brockdorff, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004971/
https://www.ncbi.nlm.nih.gov/pubmed/24790221
http://dx.doi.org/10.1242/jcs.140020