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Tuning the electrical properties of the heart by differential trafficking of K(ATP) ion channel complexes

The copy number of membrane proteins at the cell surface is tightly regulated. Many ion channels and receptors present retrieval motifs to COPI vesicle coats and are retained in the early secretory pathway. In some cases, the interaction with COPI is prevented by binding to 14-3-3 proteins. However,...

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Detalles Bibliográficos
Autores principales: Arakel, Eric C., Brandenburg, Sören, Uchida, Keita, Zhang, Haixia, Lin, Yu-Wen, Kohl, Tobias, Schrul, Bianca, Sulkin, Matthew S., Efimov, Igor R., Nichols, Colin G., Lehnart, Stephan E., Schwappach, Blanche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004980/
https://www.ncbi.nlm.nih.gov/pubmed/24569881
http://dx.doi.org/10.1242/jcs.141440